Cardiovascular Pharmacology

CARDIOVASCULAR & adenylic acid; HAEMOPOEITIC SYSTEM 1. DRUGS USED IN C.H.F. Drugs employ in C.H.F. are (5 Ds): 1. Digitalis group of medicates e.g. Digitoxin, digoxin 2. Dopamine & Do scarceamine (sympathomimetics) 3. Diesterase (phosphor-diesterase) inhibitors e.g. Amrinone, Milrinone 4. Dilators of both arterioles and venules (decrease CHF mortality also) i. brainiac inhibitors e.g. Captopril, Enalapril ii. Dihydrallazine + Isosorbide dinitrate 5. Diuretics kindred loop-the-loop diuretics, thiazides & atomic number 19 sparing diuretics 2. DRUGS USED IN ARRHYTHMIAS I.Drugs for supraventricular arrhythmias: AAdenosine BBeta-blockers e.g. Propanolol CCalcium acquit blockers e.g. verapamil DDigoxin II.Drugs for ventricular arrhythmias: Lignocaine and Mexiletine. LIGNOCAINE is the main drug used. Its features are: L topically administered as local anaesthetic. I Inactive orally so G Given I.V. for anti-arr hythmic action, which is due to N Na+ channel finish which occur in O Only inert dry land of Na+ channels. C CNS ramp effects like convulsions occur on high doses. A Action lasts simply 15 minutes due to speedy redistribution.

I Inhibits Purkinje fibers and ventricles but N No effect on AVN & SAN, so E Effective in ventricular arrhythmias only (Not supraventricular). urgency uses like to prevent arrhythmias following Ac. M.I.. cardiac surgery and digitalin toxicity. III.Drugs for both supraventricular and ventricular arrhythmias: Quinidine, Procainamide, Disopyramide, Propafenone and Amiodarone. AMIODARONE is the drug with! prominent actions. A Antiarrhythmic. M Multiple actions i.e. block k+, Na+, Ca++ channel & beta receptors. I Iodine containing (so numerous interfere with thyroid functions). O viva voce used mainly. D Duration of action is very big (t1/2 3-8 weeks ). A APD & ERP increases (so conduction decreases & humble ectopics). R unsusceptible AF, VT &...If you want to get a full essay, severalize it on our website: BestEssayCheap.com

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